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Sunday brings the inaugural Wear-Tyne derby since 2024, but who will emerge victorious – the Black Cats or the Magpies?
"Throughout the majority of last season, no one would have predicted Sunderland earning promotion and challenging with Eddie Howe's Newcastle, much less being above them in the table," commented pundit Chris Sutton.
"The situation is very different now, and the way Sunderland play leads me to believe they've got a real chance."
The analyst is providing scoreline guesses for all 380 Premier League games this season, against artificial intelligence, readers and a variety of guests.
For week 16, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the national gaming squad – the Football Association's official esports team – at the gaming title digital Euros finals tournament, which takes place at Twickenham Stadium on Saturday.
You can watch Uefa's YouTube, IG Live and TikTok channels, as well as EA Sports FC Twitch and YouTube and England's Twitch.
Are you in alignment with their predictions? You can make your own guesses below.
The fan-favourite scoreline selected for each game is used in the scoreboards at the end of this page.
A correct result (picking a win, draw or defeat) is worth 10 points. A perfect prediction earns forty points.
Ray, who competes for his club side and Manchester City as well as England, is entering the fray at the eEuros finals after passing the qualification rounds.
The final eight competitors will fly the flag at the finals in a straight knockout, competing for a six-figure prize fund and a prestigious spot in the world finals play-offs, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"My mindset is really good for it," Ray stated. "There's a really good coach with me and preparation has been going well.
"It is invariably an honour to play for your country. Of course when you are younger, you imagine doing it as an professional footballer, but when you pursue a career in this job and there is an chance to represent England, putting the shirt on is something unique.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"In my opinion he is the best player in the world so defeating him in a tournament like this just provides a massive injection of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were excellent against Arsenal at the end of November, when they got a draw after being reduced to 10 men, and I was thinking here we go, they could possibly be title contenders.
Since then, however, they were beaten physically by Leeds, looked flat against Bournemouth and this week got beaten by Atalanta in the Champions League.
So manager Enzo Maresca desperately requires a win here to restore momentum, but it will be a challenge because the Merseyside club are such a potent team.
Two of their stars are playing really well and Everton have got a bit of a positive run at the moment.
On form you would likely back the visitors, while the most prudent prediction would probably be a draw, but I'm going against logic.
The Blues have failed to given me any real reason to back them recently, but I just have a hunch they will take this one because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be intriguing to see what we get from Liverpool.
It was great to see for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the stuff with Mohamed Salah this week.
Slot shouldn't need to put up with that nonsense. I know Salah has been a great for the club but fundamentally Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond and two up top.
Everyone is going to be talking about whether Salah is back for this game, but the only way he is going to be brought back into the fold is if he says sorry.
Slot's primary concern will be on winning this game, but it is a difficult fixture.
It's fair to say it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their efforts at the San Siro will have drained them.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do fancy get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
Aside from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
The pattern suggests that tendency to continue on Sunday, and their lack of freshness is likely to be a significant issue in how this game goes because of their rivals' intensity.
We saw how relentless Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Many pundits talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays next to him, has also been one of the signings of the season and warrants praise too.
I am expecting this being the best game|most exciting fixture